Search Articles

clear search terms

LDL: truthfully NOT the “bad” cholesterol (continued)

Last week’s Clinical Tip was a provocative myth-buster for many, so this week, I’m continuing our conversation about LDL pearls.  Next week, we’ll dive into some surprising truths about HDL.  If you missed last week’s LDL feature, please click here to watch.

In today’s video, we take a quick dive into the concept of LDL receptor sensitivity…a great reminder that hormone function in the body depends on many more factors than just the simple levels of hormone in blood.  I also give you a high level introduction to alternative labs for getting at “the devil in the detail” regarding cholesterol and its relative contribution (or not) to cardiovascular disease risk.  We cover all these details in depth in our Cardiovascular Myths and Truths Clinical Course, but I want you to be aware of some key pearls.  Did you know that receptor sensitivity plays a critical role on whether or not LDL is pulled out of the blood (thus making labs look more optimal)?  What markers do you focus on the most in a conventional lipid panel?

Thank you so much for being a part of this movement!

Warmly,

 

 

 

 

 

P.S.  If you are passionate about transforming healthcare through the power of functional medicine, we encourage you to learn more about our training program here.

To receive clinical tips like this one right to your inbox, click here to receive our weekly newsletter.

Like us on Facebook to stay connected to our rich (free!) content and be notified of our popular, monthly Facebook Lives.

Subscribe
Notify of
guest
6 Comments
Inline Feedbacks
View all comments

Zarya Rubin

In a client with decreased thyroid function along with elevated LDL cholesterol, when do you retest and expect to see a drop in LDL as thyroid function comes up? What margin of LDL elevation is attributable to hypothyroidism?

Garey Simmons
Garey Simmons

So my question is how to help my LDL to be larger and puffy and increase my HDL. I’ve tried Niacin and exercising more but …. there must be something else.
Interconnectedness sidebar: This summer I had two extended gout flare-ups.

SAFM Team
Reply to  Garey Simmons

Indeed high dose niacin and regular exercise, especially weight lifting can be very effective in bringing up HDL and lowering LDL levels. In addition to that, you may want to try increasing the omega 3 fatty acids intake via fish oil or algae oil even up to 1500 mg of combined EPA and DHA twice a day. While you’re increasing the omega 3s it’s important to avoid all typically processed oils, especially those that are not labeled as ‘cold-pressed’ as this means they are chemically leached. Transresveratrol (250 mg/d) could also be a helpful addition to decrease the effects of the oxidative stress coming from the systemic inflammation while you’re working on its root cause(s). Also, since you mention gout it’s important to remember that even low-level insulin resistance can be the driver for gout and for systemic inflammation resulting in small LDL particles and low HDL levels. Thus, it would make a lot of sense to investigate what your particular body needs to reverse this process.

Eva Bartos
Eva Bartos

Hi. Tracy mentioned looking at the triglyceride to HDL ratio. My question is, what is the optimal range when looking at triglyceride/HDL ratio?

Thank you so much in advance.

SAFM Team
Reply to  Eva Bartos

Optimal triglyceride/HDL ratio is typically below 2.0
You may appreciate these references for a deeper dive as to why that is the case:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677623/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711654/